

Low-Grade Squamous Lesions: LSIL and ASCUS
Low-grade squamous intraepithelial lesion (LSIL) in cytology encompasses the histological finding of both HPV effect and CIN1.
A cytological diagnosis of LSIL is a strong indicator of histological LSIL, while ASC-US (atypical squamous cells of undetermined significance) suggests the possibility of histological LSIL.
Both LSIL and ASC-US are considered to be a low grade result and are managed using the same clinical approach.
To complete this unit
1. Listen to the NCPTS PowerPoint talk on low-grade squamous intraepithelial lesions
2. Read the NCPTS Cytomorphology Notes on LSIL for Years 1-2 Registrars
3a. Test yourself with the practice MCQS
3b. Test yourself with the practice slides
Next steps
6. Attend the Year 1-2 NCPTS workshop
7. Take the NCPTS assessment test at the end of the workshop to see how much you have learned